The official statement from Adobe is that Mavericks and Adobe Creative Suite 6 and Creative Cloud play nice together. In fact, they claim compatibility back to CS3.

I had to re-enter username & password for the Creative Cloud app after upgrading to Mavericks, InDesign runs horribly, and Adobe Illustrator opens on an old MacBook Air, but not on a brand new iMac with the exact same apps & fonts installed. Previously, Creative Cloud was running perfectly fine.

I’ve also come across dozens of other apps that are now broken, such as two different screen capture apps.

I would say if you haven’t installed Mavericks on your main rig, don’t do it yet.